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Most tirzepatide side effects especially GI events like nausea, diarrhea, and constipation peak in the first 1 to 2 weeks of starting and after each dose increase

Risk factors include: a history of pancreatitis gallstones high triglyceride levels heavy alcohol use If acute pancreatitis is suspected, Mounjaro should be stopped and you should see a doctor

Cagrilintide is also studied in combination with semaglutide (the investigational pairing known as CagriSema ), where trials have reported substantial weight reductions beyond either agent alone [5] [6]

If you have a history of mental health conditions, it's important to talk to your healthcare provider before starting medications like Semaglutide or Tirzepatide