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Tirzepatide , on the other hand, is a dual agonist that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

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GLP-1 receptor agonists are drugs that mimic this hormone, signaling the brain to reduce hunger and make other metabolic changes

It is with deep sadness that we share the news of the passing of Joel Habener, MD, an extraordinary physician-scientist, mentor, and beloved member of our Mass General Brigham community whose discoveries transformed the field of endocrinology and the care of millions of patients worldwide

In short, while theres still so much that needs sorting out, weve got a breakthrough family of drugs that are already exceeding lofty expectations
