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However, persistent or severe bruising, particularly if accompanied by unusual bleeding elsewhere, warrants medical review to exclude underlying haematological disorders
TGF-3 also plays a crucial role in UF-associated HMB, leading to the reduced expressions of thrombomodulin, PAI-1, and ATIII in the endometrium, likely contributing to menorrhagia (Sinclair et al., 2011)
(New England Journal of Medicine, 2023)
