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But they are expensive, with annual list prices as high as $16,000 and net prices, after discounts, of $7,000 to $9,000, according to a study released in April by the Institute for Clinical and Economic Review

2013;110(22):9066-9071 doi:10.1073/pnas.1219451110 (Animal) Depommier C, Everard A, Druart C, et al
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Gastrointestinal side effects were most common: nausea (43%), diarrhea (33%), constipation (25%), and vomiting (21%) at the 12mg dose

Timeline of body composition shifts Weeks 1 through 4: minimal measurable composition change
