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Abstract This large community-based cohort study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically Liraglutide and Semaglutide, on the risk of developing psychiatric conditions such as depression, anxiety, and suicidal behaviors in patients with obesity

doi: 10.2337/db20-924-P

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Pharmacogenomics, other phenotypes we don't really know why some people only lose 5% where some people are super responders and losing 30% of their body weight

At baseline, the mean body weight was 102 kg, HbA1c was 70 mmol/mol, TC was 4.32 mmol/L, LDL was 2.38 mmol/L, and HDL was 1.06 mmol/L