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A Way Forward 3

A new retrospective study from UCLA, published in ACR Open Rheumatology , suggests that GLP-1 RAs such as semaglutide and tirzepatide not only lower body weight and improve metabolic health, but also reduce RA disease activity and patient-reported pain

In addition to a regulatory role in intrarenal RAS homeostasis, megalin seems also to indirectly contribute to atherosclerosis development increasing renal ANG II levels (40)

A follow-up DEXA might show that 22 of those pounds were fat loss and 8 were lean mass loss

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