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GLP-1 agonists like semaglutide reduce caloric intake through appetite suppression while improving insulin sensitivity

The company references a figure of "20-25% average body weight loss" for tirzepatide

Thirty-five trials with 13 treatments lasting a minimum of 8 weeks were included, and GLP-1R agonists were associated with modest improvements in total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels, whereas there was no change in high-density lipoprotein cholesterol

It is probably not likely that a doctor will prescribe Tirzepatide to people who do not have type 2 diabetes or weight-related issues

Among adults who take the medications, about half say its difficult to afford the cost, according to a May 2024 survey by the health policy group KFF