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However, the goal of a comprehensive weight management programme should be to address the internal drivers sufficiently that medication can be reduced or discontinued while maintaining results

Weight & glycemic control: robust randomized control trials (RCTs) show large, clinically meaningful weight loss and A1C reduction with semaglutide and tirzepatide for people with obesity and/or type 2 diabetes

Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota

Lammert A, Kiess W, Bottner A, Glasow A, Kratzsch J

In the dulaglutide head-to-head comparisons with exenatide twice daily and liraglutide, GI side effects were similar between groups [5,6] Exenatide bid & weekly, Liraglutide & Dulaglutide have themost weight reduction effect