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(B-C) Co-IP assays were conducted to investigate the interaction between endogenous NEDD4 and YAP1 in primary astrocytes

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This staged approach improves tolerability and adherence, though it means the full therapeutic effect develops more gradually

Therefore, we aimed to determine whether GLP-1RAs, compared with sodiumglucose cotransporter 2 (SGLT2) inhibitors, metformin or other second- or third-line glucose-lowering medications, are associated with a lower rate of new-onset adverse cardiovascular events (CVEs) among patients with NAFLD and type 2 diabetes