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Some long-acting formulations that are typically injected once weekly include Semaglutide, Dulaglutide, EX-LAR (long-acting release formulation of Exenatide), and PEX-168 (polyethylene glycol Loxenatide) [2]

13 Table 2: Signs and Symptoms of Semaglutide Overdose 12 Feeling lightheaded or dizzy Feeling shaky or jittery Sweating, chills and clamminess Irritability or impatience Headache Weakness Fatigue Nausea and/or vomiting Seizures Altered Mental Status Syncope/Near Syncope Hypotension Lastly, it is important to note that most calls for help related to semaglutide overdoses are from adults ages 40-70, with the largest group in the 60 to 69 range

A rare case of dulaglutide-associated angioedema in a male patient

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Its possible to reduce the risks by eating enough protein and engaging in strength-building exercises, such as weight lifting