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Wellbutrin lowers the seizure threshold, and the risk increases with higher doses, rapid dose escalation, or in patients with predisposing factors (eating disorders, head trauma, alcohol withdrawal, or concurrent use of other medications that lower seizure threshold)

In a large study directly comparing the two, both medications helped participants achieve meaningful weight reduction

When traveling, patients should use insulated medication travel cases with gel packs specifically designed for temperature-sensitive medications

Calories in, calories out never worked for me

However, these prescription treatments often carry significant costs and may cause side effects such as nausea and digestive discomfort, limiting their suitability for some individuals