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Do not restart tirzepatide and contact your healthcare team if you cannot keep fluids down for more than 4-6 hours, experience persistent vomiting for over 24 hours, have severe abdominal pain, or have blood glucose levels consistently above 300 mg/dL

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If you are unsure, call your compounding pharmacy and ask them to confirm

At higher effective drug exposure, these musculoskeletal symptoms could become more frequent or more intense, further reducing quality of life and exercise tolerance

Anderson, J.W., Greenway, F.L., Fujioka, K., Gadde, K.M., McKenney, J