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Although no comprehensive studies on BBR elimination in humans have been conducted [22], data from rat models suggest that approximately 22.83 % of the administered dose can be recovered, with berberrubine and thalifendine being the main excreted metabolites [22]

NICE guidelines on obesity management (NG246) do not recommend probiotics as an intervention for weight loss, focusing instead on evidence-based approaches including dietary modification, physical activity, behavioural interventions, and where appropriate, pharmacological treatments or bariatric surgery

You could be under nourishing yourself, but more often than not

Instead, they advise that imaging teams carefully document patients medication histories to inform interpretation while formal guidance is developed

Sharma, A., Varghese, R