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The law (Medicare Modernization Act of 2003) explicitly excludes drugs when used for weight loss, weight gain, or anorexia. (ASPE) Some proposed changes (including reinterpreting the exclusion for obesity) were considered , but in April 2025 those were not finalized
A multicenter, randomized, double-blind, multiple dose-escalation study showed that after 4 weeks of treatment of PEX-168 with different doses, the weight decreased by -0.8-1.8kg

Front Neurosci 9:111 Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM (1994) Positional cloning of the mouse obese gene and its human homologue
Read on as we break down the prices for the Wegovy pill, with and without insurance

In studies published in 1993 by Michael Nauck and colleagues in Gttingen, i.v