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Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor
While effective, these agents may also reduce metabolic rate over time, which can limit sustained fat loss

To help with nausea, eating smaller, more frequent meals vs eating a large meal can help

doi: 10.1152/ajpgi.00372.2013

That statement is as well-supported as any other finding in the field
