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Future randomised controlled trials should specifically evaluate the effectiveness of novel AOMs for long-term weight management in older adults with obesity, carefully considering the impact on body composition and functional ability, as well as health economics.

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World Obesity Federation: [3] 2 Diet drugs are pulled off market, Washington Post, 16 September 1997: [4] The Global Use of Medicines 2024 - IQVIA [5] [6] In heavyweight obesity fight, Eli Lilly launches Mounjaro head-to-head trial against Novo Nordisks Wegovy

By Sabina Paglialunga, PhD & Aernout van Haarst, PhD Senior Directors Scientific Affairs Glucagon-Like Peptide-1 (GLP-1) receptor agonists first came to the market in 2005 as a type 2 diabetes mellitus treatment, and they have been making headlines again for their weight reduction effects