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In a clinical study by Malaguarnera et al (277), Bifidobacterium bifidum was found to markedly improve lipids, IR index, liver tissue inflammation and liver fibrosis in patients with MASH

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After 2 weeks of treatment, mice treated with GLP-1MK-801, as well as those subjected to calorie restriction or GLP-1 monotherapy, demonstrated enhanced glucose tolerance compared with mice that were treated with the vehicle or MK-801 monotherapy (Extended Data Fig