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N Engl J Med 2003;348:383393 [DOI] [PubMed] [Google Scholar] 28.Saraiva FK, Sposito AC

A 2024 systematic review found that, on average, tirzepatide raised resting heart rate by around 1.8 beats per minute compared with placebo, with a slightly larger effect at the 15 mg dose

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For more information on GLP1R agonists and their impact on perioperative care, check out Anesthesia Updates on the NYSORA Anesthesia Assistant App

GLP-1 drugs were developed and FDA approved for specific medical indications, including type 2 diabetes management and, for certain products, chronic weight management in obese adults and other eligible patients