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The primary enforcement concerns have centered on marketing claims that imply equivalence to FDA-approved products and branding practices that obscure the identity of the actual compounder

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Physiol Rep 5(7):e13250 Musso C, Cochran E, Moran SA et al (2004) Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective

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NICE guidance (TA875) recommends its use within specialist weight management services, with specific NHS commissioning criteria (typically BMI 35 kg/m with comorbidity, with exceptions for BMI 30-34.9) and a maximum treatment duration of 2 years