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Description
Adipose tissue failure forces the spillover of excessive free fatty acids (FFA) into the systemic circulation, causing ectopic fat deposition in non-adipose organs, including the skeletal muscle and, critically, the liver ( de novo lipogenesis and endogenous glucose production, thereby driving both hepatic steatosis and hyperglycemia
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It is argued that TAME trial outcomes will give more insight on whether metformin decreases the risk of developing age-dependent diseases, excluding diabetes, in non-diabetic individuals, and potentially provide a tool to target aging itself and not related diseases individually (261)
The needs are complex
Fiyatlar, SGK, yan etkiler ve doktora gitmeden nce bilmeniz gerekenler
