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Emerging controversies boil down to the outlook for prescriptions, payors, price and pipeline
Take a big grain of salt when comparing across trials
When treatment ends abruptly, these appetite-regulating mechanisms reset within weeks
Jiao Y, Chen X, Liu L, Lu Y, Gao M, Wang Q, et al
Worryingly however, 26.8% of patients had to discontinue the trial due to the severity of side-effects, although it must be noted that this was in part due to the lack of a run-in (A time frame where drug dosage is started from a low dosage and then escalated over time until the highest tolerable dose for the patient is reached) [40]
