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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Zhang Z., Li J., Jiang X., Yang L., Lei L., Cai D., Zhang H., Chen H

In addition to promoting hypoglycemic effects, they can increase the number of cells in the pancreas, block cell death, and boost insulin production [90], [91]

Regular monitoring by a healthcare provider proves essential to manage these risks effectively

Metformin, by contrast, is often the go-to option for managing moderate insulin resistance in PCOS

Pica behavior is a validated endpoint to assess the ability of a compound to induce nausea/malaise in non-vomiting species, as mouse, based on the monitoring of non-nutritive (kaolin) food intake, as an index of gastrointestinal discomfort 43,44