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Those using semaglutide also experienced an average reduction in their WOMAC pain score of 41.7 points, whereas the untreated group had an average decrease of 27.5 points

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Personalizing Your GLP-1 Therapy with PlexusDx Genetic Testing PlexusDx's Precision Peptide Genetic Test examines your unique variants in GLP-1 receptor genes, FTO appetite-regulation genes, and GIPR pathways that influence how your body responds to semaglutide

For example, a recent analysis of the FDAs reporting system (FAERS) highlighted that taste disturbances (dysgeusia) are noted more frequently by patients using GLP-1RAs in everyday practice than in clinical trial reports (161)

It can happen because appetite falls so much that the patient unintentionally consumes too little protein and too few total nutrients