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Finally, it is important to note that the popularity of the drugs is ballooning (Montero, et al., 2024

This raises the possibility that GLP-1 medicines may reduce neuroinflammation both directly, through actions on neurons, and indirectly, by lowering systemic inflammation that contributes to neuroinflammatory processes

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There are many oral and injectable options now that are FDA-approved, so its best to stick with medications that have been assessed by the standard safety/efficacy channels. On the other hand, many patients are getting results with compounded semaglutide and tirzepatide

In people without diabetes, some trials have explored dapagliflozin as a monotherapy or in combination with other weight loss agents have been explored