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These non-scale victories (NSVs) like better-fitting clothes, improved sleep, or reduced joint pain can be even more rewarding
There appears to be a direct anti-inflammatory effect independent of metabolic changes
Median follow-up time of these studies ranged from 1.6 to 5.4 years
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Overall, these results indicate GLP-1RAs can influence a number of proteinopathies across disease models, although more understanding is required to determine when in the course of disease proteostasis can be modulated to bring about reduced neuronal loss and clinical benefit
