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Quigley K, Goya R, Meites J (1987) Rejuvenating effects of 10-week underfeeding period on estrous cycles in young and old rats

Takeaway: Supplements work best as prevention rather than rescue

doi: 10.1016/0002-9610(75)90360-8

And since reduced food intake on tirzepatide can lower dietary magnesium intake, supplementation addresses a potential deficiency at the same time
