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Do not rely solely on creatinine-based eGFR during rapid weight loss

Better metrics during tirzepatide treatment: Body composition measurements (DEXA scan, bioimpedance scale, or even waist-to-hip ratio) Strength benchmarks (can you lift what you lifted last month?) Energy diaries (rate energy 1 to 10 daily to track trends) Grip strength (a reliable proxy for overall muscle function) Walking speed (declining walking speed correlates with lean mass loss) If your weight is going down but your strength is maintained and energy is stable, you are losing primarily fat

But for many patients, the most disruptive side effect isnt the nauseait is the constipation

Hebsgaard, J

[DOI] [PMC free article] [PubMed] [Google Scholar] 178.Poljsak B., Ribari S., Milisav I