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N Engl J Med 2017;377:122839.PubMedPMC 69

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Structural figures were prepared in UCSF Chimera v1.15 and PyMOL 2.1 ( cAMP accumulation assay For GIPR, GLP-1R and GCGR, multi-targeting agonist stimulated cAMP accumulation was measured by a LANCE Ultra cAMP kit (PerkinElmer)