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Step 2: Preparation of compound of formula-7a EDC.HC1 (17.45 gm) and HOBt (8.14 gm) were added to a pre-cooled mixture of compound obtained in step-1 and tetrahydrofuran (150 ml) at 0-5C

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(18) Concomitant use of medications that cause weight gain or weight loss

Its safety in individuals over 75 years of age is not established
