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A meta-analysis of three studies including 1,119 participants found that individuals with PAM variants responded less well to GLP-1 receptor agonists and were less likely to lower their HbA1c, a measure of long-term blood sugar

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If the results seem sound, says Albert, a former president of the American Heart Association, the study opens the door for a wider range of folks benefiting from this medication

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What matters more is the overall quality of your diet, portion sizes, and total caloric intake rather than avoiding bread entirely