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Then, the animals proceeded to a PR schedule of reinforcement where they were tested across 4 sessions at variable doses of fentanyl (0-10 g/kg/inf, i.v.) in a randomized order while receiving a stable dose of semaglutide (0.1 mg/kg, s.c.) or vehicle (0.9% saline, s.c.)

Then factor in any weight loss from weeks or months on the medication

Currently, allodynia is not listed as an adverse effect in the FDA-approved prescribing information for semaglutide products (Ozempic, Wegovy, and Rybelsus)

Oral Semaglutide is a groundbreaking FDA-approved medication for chronic weight management, known for its effectiveness in aiding weight loss

For more information on weight management and type 2 diabetes treatment options, schedule a consultation with a New Jersey Bariatric Center doctor to discuss your individualized needs