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In the TRIUMPH-4 trial, participants on the 12 mg dose of retatrutide lost an average of 71.2 pounds over 68 weeks

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GLP-1s work by slowing how fast your stomach empties and reducing appetite

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The endogenous half-life has also been increased through conjugation of the GLP-1 amide backbone with fatty acids, albumin, or human immunoglobulin to reduce the rate of renal elimination [42,43,44]

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