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Preclinical studies indicate that GLP-1 RAs can attenuate atherosclerosis by reducing vascular inflammation, lowering oxidative stress, and inhibiting the proliferation and activation of vascular smooth muscle cells [51, 52]

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The right drug: not every weight-loss shot is the same Right now in the U.S., the main injectable medications approved by the FDA for chronic weight management are liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound)

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When we evaluated FcRn-mediated recycling in a cell-based assay, where the receptor is embedded in the membrane, the WT fusion was recycled 1.8-fold less efficiently than unfused WT albumin, which is in line with its shorter plasma half-life