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The Downsides: Muscle Loss and Sagging Skin When using GLP-1 agonists, the weight loss process can be rapid

For these individuals, the ultra-low introduction phase (weeks 1 through 4 at 0.125 to 0.5 mg) may need to be extended to 6 or even 8 weeks

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It's a significant side effect that deserves serious attention as this medication approaches approval

(But) the older you are, the less evidence there is from any trial about you, because most of these trials havent really enrolled people over 70 or 80, so we need to continue to learn and see how this works
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