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Obesity is increasingly framed as a chronic condition requiring ongoing management rather than a finite intervention, and current guidance supports indefinite treatment for appropriate patients

doi: 10.1038/s42255-023-00931-7

While it doesnt necessarily make an oral medication less effective overall, it may delay its onset of action or require closer monitoring and potential dosage adjustments

Idris I, Abdulla H, Tilbrook S, Dean R, Ali N

They help reduce hunger, increase fullness, and improve metabolic regulation, which can make it easier for patients to sustain a calorie deficit over time
