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A modest heart rate increase of up to 6.7 bpm was noted in Phase 2 data

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Diabetologia 59(7):14121421 Tonneijck L, Muskiet MHA, Smits MM, Hoekstra T, Kramer MHH, Danser AHJ et al (2017) Postprandial renal haemodynamic effect of lixisenatide vs once-daily insulin-glulisine in patients with type 2 diabetes on insulin-glargine: an 8-week, randomised, open-label trial
