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Model Development Model development was conducted in NONMEM as follows: The structural disposition model, which was supported by graphical analysis, in particular of intravenous data, was a two-compartment model with first-order elimination

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In a substudy (n=66) evaluating bone mineralization via dual-energy X-ray absorptiometry (DEXA), increases in bone mineral density (BMD) at the lumbar spine and total body less head (TBLH) were smaller in pediatric patients treated with QSYMIA compared to those treated with placebo after 1 year of treatment

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Even though it contains the same active ingredient as Ozempic, the Wegovy pen is different