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All analyses were conducted on previously published studies and publicly available data

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Exenatide for weight-loss maintenance in adolescents with severe obesity: A randomized, placebo-controlled trial

Description of drug classesMetformin Metformin is an effective drug, affording an expected mean HbA1c reduction of 1.3% to 2.0%, particularly when routinely used as the first option at the diagnosis of DM2 with elevated HbA1c levels.21 Despite extensive experience in the use of the drug, we have only recently advanced in our knowledge of its mechanism of action

GLP-1 receptor agonists are a novel class of pharmacological agents for obesity and T2D