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Revisiting the 6-month BT-first recommendation Clinical practice guidelines have evolved towards a complications-centric approach to obesity management, yet outdated recommendations regarding intervention timing persist

More evidence is needed to clarify the ideal duration that an AOM should be given initially before the first interval, but longer compliance with anti-obesity agents from the outset does result in reduced weight regain following cessation [97]
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PDE5 inhibitors like sildenafil and tadalafil remain first-line treatment with 50-65% success rates in diabetic men

Healthcare professionals can customize treatments based on individual symptoms
