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Another significant contact at the N-terminus of the peptide is mediated through E9 P that participates in van der Waals interactions with Leu388 and Ser392 of TM7, while it is also positioned to potentially form hydrogen bonding with conserved polar residues R190 on TM2 and Y145 on TM1 (Fig

[DOI] [PubMed] 144.Diabetes Control Complications Trial Research Group Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial