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Conclusions In this post hoc analysis of SUSTAIN 6, once-weekly semaglutide vs placebo reduced the risk of MACE in all subjects included in the trial, regardless of gender, age, or baseline CV risk profile

Many endocrinologists are now recommending GLP-1 drugs as first line injectables therapy over the insulin for many Type II diabetes as GLP-1 benefits outweighs Insulin

this finding should be interpreted cautiously given the retrospective design, active and non-inert comparator, and likelihood of residual confounding
