first large study of glp-1 receptor agonists during pregnancy New developments in agonist therapy for gestational diabetes: Systematic review on liraglutide, semaglutide, and exenatide from ClinicalTrials.gov Navigating GLP-1 and Pregnancy: Insights,
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Conversely, another study has revealed that administration of cyclopamine partially counteracts the protective effects of GIMAP7 knockout on rats with PCOS with increased ROS levels (318)

Patients should contact their healthcare provider if they experience severe or persistent vomiting that prevents adequate fluid or medication intake, as this can lead to dehydration and electrolyte imbalances
Common Nutrient Deficiencies on GLP-1 Meds Due to reduced intake and slowed digestion, you may become deficient in: Protein (key for muscle and metabolic health) Vitamin B12 (energy, cognition) Iron (oxygen transport, mood) Magnesium (nervous system, sleep, blood sugar) Vitamin D (immune, hormones, bones) Symptoms to watch for: Hair loss, fatigue, low motivation, weakness, poor recovery, sleep disruption, irritability

DPP-4 plays a critical role in maintaining glucose homeostasis (Figure 1)

PMID: 23771206
