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New England Journal of Medicine, 389(6), 514-526.
Glomerular hyperfiltration has been identified as a key factor predisposing to kidney disease
From physiology to therapy From physiology to therapy It is this triple actionon satiety, insulin, and digestionthat explains the success of GLP-1 mimicking drugs in type 2 diabetes and obesity (exenatide, liraglutide, semaglutide, etc.)
Moreover, because discontinuation of GLP-1RAs often leads to weight regain, these medications must be regarded as a chronic therapy to sustain weight loss and prevent associated negative health outcomes
It filtered into med spas and telehealth clinics, creating demand that some providers are aggressively trying to meet
