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Incretins, such as GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), are secreted by entero-endocrine cells of the gastrointestinal tract to stimulate glucose-dependent insulin secretion and beta-cell proliferation

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Phase 3 trials are currently running

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The Costs to Health Plans There are a variety of GLP-1 drugs on the market

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This group noted there is no evidence to suggest optimal duration of fasting

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Receptor desensitization, downregulation, and adaptation all play roles that are dose-dependent and time-dependent

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