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This approach not only enables flexibility in the choice of azide insertion sites but also supports the attachment of diverse fatty acid moieties, thereby providing a strong basis for further expanding the mutant library of tirzepatide

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On 8 November 2023, Tirzepatide, branded as Zepbound in the US, received FDA approval as the first dual-target agonist for the treatment of obesity, further highlighting its potential in medical treatment options

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