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Description
Standard dosing follows a step-up schedule, increasing from 0.25 mg to 2.4 mg, as used in most trials
[DOI] [Google Scholar] Spokoyny A

The metabolic phenotype, marked by a fourfold increased mortality risk, underscores the pivotal role of obesity and T2D in driving adverse outcomes [25]

Persistent hyperglycaemia damages endothelial cells lining blood vessels, impairing nitric oxide productiona key mediator of penile erection

Clinical trials often include pregnancy testing or contraception requirements, depending on the protocol
