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2.1.3 COL6A1 In recent years, it has been found that there is a significant effect of TME on the growth and spread of tumor cells, in which extracellular matrix (ECM) is an important component of TME, regulating the growth, invasion, apoptosis, drug resistance and metastasis of tumor cell (13)

However, the combination treatment did not produce greater weight loss than a very low-calorie diet alone

Vinegar , particularly apple cider vinegar, has been studied for its potential to improve glycaemic control and may influence GLP-1 secretion, though evidence remains preliminary