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Replace Potassium A) Oral Potassium Replacement (Preferred) Used for mild to moderate hypokalemia Safer than IV Give with food to reduce GI irritation Slow and steady correction Good for: Stable patients Ability to take orally Gradual potassium decline B) Intravenous (IV) Potassium Replacement Use only when: Severe hypokalemia Symptomatic (arrhythmias, paralysis) Cannot take oral therapy Ongoing significant potassium losses Safety points (VERY IMPORTANT): IV potassium must be given slowly Must be diluted properly Cardiac monitoring required for rapid or higher doses Never give as IV push 4

Compared with sitagliptin, oral semaglutide was more effective in HbA1c reduction and weight reduction in both Asian and non-Asian patients