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The EMA warned in October about falsified Ozempic injector pens identified at wholesalers in the EU and the UK

Common adverse effects include gastrointestinal symptomsnausea, vomiting, diarrhea, constipation, and abdominal painwhich are generally dose-dependent and may diminish over time with continued use

Paixao also notes potential implications for kidney transplant eligibility

Any use should be guided by a licensed clinician, with informed consent and clear expectations about what is known and what is still being learned

Heres what the research and my clinical experience reveal: Semaglutide is a well-established option with: Weekly injections Proven safety profile Average weight loss of 15-20% of body weight Effective appetite suppression Improvements in cardiovascular health markers Tirzepatide offers: Weekly injections Potentially greater weight loss (16-22.5% of body weight) Dual-action mechanism Similar side effect profile to semaglutide Enhanced metabolic benefits In a recent head-to-head trial , tirzepatide demonstrated superior weight loss compared to semaglutide, with participants losing an average of 20.2% versus 13.7% of their body weight at 72 weeks