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Description
Although the use of GLP-1 RAs prior to EGD or colonoscopy has resulted in poor outcomes in terms of poor visibility/preparation scores and the need for aborted/repeated procedures, one study showed better outcomes with concurrent EGD and colonoscopy

Traditional sublingual drops often slide off the tissue quickly, resulting in the medication being swallowed rather than absorbed through the mucous membranes

No official prescribing information has been published for the compounded vial format
Does Semaglutide Cause Diarrhea

While semaglutide and tirzepatide both reduce appetite through similar pathways, alternating between them is not a standard clinical strategy and carries distinct safety and efficacy considerations that PlexusDx providers carefully evaluate for each patient
